Daprodustat


CAS No. : 960539-70-2

(Synonyms: GSK1278863)

960539-70-2
Price and Availability of CAS No. : 960539-70-2
Size Price Stock
5mg $88 In-stock
10mg $140 In-stock
25mg $230 In-stock
50mg $400 In-stock
100mg $660 In-stock
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Cat. No. : HY-17608
M.Wt: 393.43
Formula: C19H27N3O6
Purity: >98 %
Solubility: DMSO : 19.5 mg/mL (49.56 mM; Need ultrasonic and warming)
Introduction of 960539-70-2 :

Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease. In Vitro: GSK1278863 is an orally administered small-molecule PHI, and stimulates endogenous EPO synthesis and induce effective erythropoiesis[1]. GSK1278863 has been shown to increase erythropoietin levels, leading to increases in hemoglobin, hematocrit and red blood cell numbers[2].

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