Lorediplon


CAS No. : 917393-39-6

917393-39-6
Price and Availability of CAS No. : 917393-39-6
Size Price Stock
5mg $32 In-stock
10mg $50 In-stock
25mg $115 In-stock
50mg $200 In-stock
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200 mg Get quote
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Cat. No. : HY-19371
M.Wt: 394.42
Formula: C20H15FN4O2S
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 917393-39-6 :

Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. Target: GABA Lorediplon is a drug for the treatment of insomnia, has been successfully completed with a best-in-class efficacy profile in terms of maintaining sleep and sleep quality, Lorediplon targets GABAA. [1] Lorediplon demonstrates a minimum of 10-fold and 6-fold increase in potency (respectively) in the spontaneous motor activation studies. At concentrations of 1.2mg/kg, Lorediplon demonstrates a 57%increased effect on Slow Wave Sleep (SWS), when compared with a placebo.[2]

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