PARP1-IN-8


CAS No. : 836640-15-4

836640-15-4
Price and Availability of CAS No. : 836640-15-4
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5mg $300 In-stock
10mg $480 In-stock
25mg $950 In-stock
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Cat. No. : HY-147030
M.Wt: 403.86
Formula: C23H18ClN3O2
Purity: >98 %
Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Introduction of 836640-15-4 :

PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549[1]. IC50 & Target: IC50: 97  ±  0.90 nM (PARP-1)[1] In Vitro: PARP1-IN-8 (compound 11c) (0-10 μM, 24-48 h) shows significantly potent anti-proliferative activity against A549 cells[1].

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