NSC348884


CAS No. : 81624-55-7

81624-55-7
Price and Availability of CAS No. : 81624-55-7
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10mg $115 In-stock
25mg $230 In-stock
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100mg $550 In-stock
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Cat. No. : HY-13915
M.Wt: 636.79
Formula: C38H40N10
Purity: >98 %
Solubility: DMSO : ≥ 34 mg/mL (53.39 mM)
Introduction of 81624-55-7 :

NSC348884 is a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis, inhibits cell proliferation at an IC50 of 1.7-4.0 μM in distinct cancer cell lines. Target: nucleophosmin in vitro: NSC348884 is a putative nucleophosmin small molecular inhibitor that disrupts a defined hydrophobic pocket required for oligomerization. NSC348884 disrupts nucleophosmin oligomer formation by native polyacrylamide gel electrophoresis assay. NSC348884 upregulates p53. NSC348884 induces apoptosis.[1]

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