CBR-5884
CAS No. : 681159-27-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $79 | In-stock |
| 10mg | $132 | In-stock |
| 25mg | $277 | In-stock |
| 50mg | $488 | In-stock |
| 100mg | $871 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100012 |
| M.Wt: | 336.39 |
| Formula: | C14H12N2O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (148.64 mM; Need ultrasonic) |
CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1]. IC50 & Target: PHGDH, serine synthesis[1] In Vitro: CBR-5884 (15 or 30 μM; 3-5 days) selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis.
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