Size | Price | Stock |
---|---|---|
1000g | $53 | In-stock |
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Cat. No. : | HY-Y1314 |
M.Wt: | 94.13 |
Formula: | C2H6O2S |
Purity: | >98 % |
Solubility: | H2O : 50 mg/mL (ultrasonic) |
Dimethyl sulfone (Methyl Sulfonyl Methane) is a metabolic product of endogenous methanethiol metabolism and intestinal bacterial metabolism. Dimethyl sulfone inhibits choriocapillary endothelial (CCE) cell proliferation, also has many biological effects, including antiinflammatory, antioxidant, and local anesthetic effects that could be neuroprotective[1][2][3].
In Vitro:Dimethyl sulfone (25 mM/mL for 15.5 μL/mL; 24 h) inhibits the proliferation of cultured bovine choriocapillary endothelial (CCE) cells[2].
In Vivo:Dimethyl sulfone (for 0, 0.01, 0.03, 0.1, 0.3 and 1.0 mL; i.p.; single dose) shows neuroprotective effect with significant infarction volume reduction in ischemia rats[3].
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