DBCO-Val-Cit-PABC-PNP


CAS No. : 2994332-18-0

2994332-18-0
Price and Availability of CAS No. : 2994332-18-0
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1mg $90 In-stock
5mg $260 In-stock
10mg $380 In-stock
25mg $800 In-stock
50mg $1280 In-stock
100mg $2100 In-stock
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Cat. No. : HY-130937
M.Wt: 859.92
Formula: C46H49N7O10
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 2994332-18-0 :

DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Val-Cit-PABC-PNP is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

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