GAK inhibitor 49 (hydrochloride)
CAS No. : 2930378-91-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $148 | In-stock |
| 10mg | $249 | In-stock |
| 25mg | $409 | In-stock |
| 50mg | $574 | In-stock |
| 100mg | $740 | In-stock |
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| Cat. No. : | HY-124793A |
| M.Wt: | 406.86 |
| Formula: | C20H23ClN2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2[1]. In Vitro: GAK inhibitor 49 (compound 49) hydrochloride shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC50s of 28, 63 and >100μM, respectively[1].
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