BI-3231
CAS No. : 2894848-07-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $195 | In-stock |
| 10mg | $305 | In-stock |
| 25mg | $495 | In-stock |
| 50mg | $690 | In-stock |
| 100mg | $970 | In-stock |
| 250mg | $1460 | In-stock |
| 500mg | $2100 | In-stock |
| 1g | $2950 | In-stock |
| 5 g | Get quote | |
| 10 g | Get quote | |
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| Cat. No. : | HY-148814 |
| M.Wt: | 380.37 |
| Formula: | C16H14F2N4O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C) |
BI 3231 is a potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases[1]. IC50 & Target:hydroxysteroid 17β-dehydrogenase 13 (HSD17B13)[1] In Vitro: BI 3231 demonstrates high metabolic stability in liver microsomes and moderate metabolic stability in hepatocytes[1]. In Vivo: BI 3231 is rapidly cleared from plasma, considerable hepatic exposure was maintained over 48 h[1].
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