DBCO-PEG4-GGFG-Dxd


CAS No. : 2694856-51-2

2694856-51-2
Price and Availability of CAS No. : 2694856-51-2
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5mg $850 In-stock
10mg $1450 In-stock
25mg $2320 In-stock
50mg $3000 In-stock
100mg $3900 In-stock
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Cat. No. : HY-134723
M.Wt: 1375.45
Formula: C72H79FN10O17
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 2694856-51-2 :

DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG[1]. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke[1].

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