Lenalidomide-6-F


CAS No. : 2468780-87-0

2468780-87-0
Price and Availability of CAS No. : 2468780-87-0
Size Price Stock
100mg $36 In-stock
250mg $72 In-stock
1g $183 In-stock
5g $638 In-stock
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Cat. No. : HY-138881
M.Wt: 262.24
Formula: C13H11FN2O3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 2468780-87-0 :

Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

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