PHCCC
CAS No. : 179068-02-1
| Size | Price | Stock |
|---|---|---|
| 2mg | $50 | In-stock |
| 5mg | $70 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $250 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $780 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100409 |
| M.Wt: | 294.30 |
| Formula: | C17H14N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (42.47 mM; Need ultrasonic) |
PHCCC is a Group I mGluR antagonist with an IC50 of 3 μM. PHCCC is a selective positive modulator of mGlu4 receptor. Antiparkinsonian effect[1][2]. In Vitro: PHCCC potentiated the effect of L-(+)-2-amino-4-phosphonobutyric acid (L-AP4) in inhibiting transmission at the striatopallidal synapse[2]. In Vivo: PHCCC (75 nmol/2.5 μl; intracerebroventricular) produces an antiparkinsonian effect in a dopamine depletion akinesia model[2].
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