5-ALA benzyl ester (hydrochloride)


CAS No. : 163271-32-7

(Synonyms: Benzyl-ALA (hydrochloride))

163271-32-7
Price and Availability of CAS No. : 163271-32-7
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25mg $130 In-stock
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Cat. No. : HY-133100
M.Wt: 257.71
Formula: C12H16ClNO3
Purity: >98 %
Solubility: H2O : 100 mg/mL (388.03 mM; Need ultrasonic); DMSO : 250 mg/mL (970.08 mM; Need ultrasonic)
Introduction of 163271-32-7 :

5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines[1][2]. In Vitro: 5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480[2]. In Vivo: Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels[3].

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