ALKBH5-IN-3
CAS No. : 1505579-77-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $160 | In-stock |
| 50mg | $260 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-165422 |
| M.Wt: | 272.18 |
| Formula: | C11H7F3N2O3 |
| Purity: | >98 % |
| Solubility: |
ALKBH5-IN-3 is a selective, cell active ALKBH5 inhibitor with an IC50 of 0.021 μM. ALKBH5-IN-3 stabilizes ALKBH5 in HepG2 cells, and increases m6A level in intact cells. ALKBH5-IN-3 can be used as a versatile chemical probe to explore the biological function of ALKBH5. ALKBH5-IN-3 can be used for the research of Cancer[1].
IC50 & Target:IC50: 21 nM (ALKBH5)[1]
In Vitro:ALKBH5-IN-3 (Compound 20m) (0.3-10 μM; 72 h) increases m6A levels in HepG2 cells[1].
ALKBH5-IN-3 (100 μM; 3 h) stabilizes ALKBH5 in HepG2 cells[1].
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