Exatecan Intermediate 2 (hydrochloride)
CAS No. : 2437603-23-9
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| Cat. No. : | HY-W021377A |
| M.Wt: | 286.73 |
| Formula: | C13H16ClFN2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic) |
Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1]. In Vitro:Camptothecin derivatives are a class of cytotoxic small molecules that can be used in the preparation of antibody-drug conjugates. Camptothecin derivatives generally exhibit antitumor effects by inhibiting topoisomerase I[1].
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