Protein kinase inhibitor 1 (hydrochloride)
CAS No. : 2321337-71-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $140 | In-stock |
| 25mg | $310 | In-stock |
| 50mg | $550 | In-stock |
| 100mg | $990 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-U00439A |
| M.Wt: | 419.89 |
| Formula: | C18H18ClN5O3S |
| Purity: | >98 % |
| Solubility: | H2O : 9.09 mg/mL (ultrasonic);DMSO : 8.33 mg/mL (ultrasonic) |
Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.
IC50 & Target:IC50: 74 nM (HIPK2), 136 nM (HIPK1)[1]
Kd: 9.5 nM (HIPK2)[1]
In Vitro:Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2. Protein kinase inhibitor 1 (Compound A64) is not an effective Cdk1 inhibitor (IC50 > 10 μM). A64 is moderately selective across a panel of kinases, with Kds of 3.7 nM (PIM3), 6.1 nM (CSNK2A2), 6.1 nM (CSNK2A2), 8.8 nM (DYRK1A), 9.5 nM (DAPK1), 31 nM (CSNK2A1), 37 nM (PIM1), 130 nM (DRAK2), 150 nM (CLK2), 190 nM (DRAK1), 220 nM (ULK2), 240 nM (CLK1), 250 nM (DYRK2), and 390 nM (ERK8) and IC50s of 19 nM (DYRK1A), 62 nM (DYRK1B), and 74 nM (HIPK2)[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Protein kinase inhibitor 1 (hydrochloride)
- Cat. No.:
- HY-U00439A
- Quantity:
Your information is safe with us.