Ustekinumab


CAS No. : 815610-63-0

(Synonyms: CNTO-1275; L04AC05; TT-20)

815610-63-0
Price and Availability of CAS No. : 815610-63-0
Size Price Stock
1mg $550 In-stock
5mg $970 In-stock
10mg $1550 In-stock
25mg $2950 In-stock
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100 mg Get quote
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Cat. No. : HY-P9909
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: H2O
Introduction of 815610-63-0 :

Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody. IC50 & Target:IL-12B In Vitro: Ustekinumab is a human monoclonal antibody that prevents human IL-12 and IL-23 from binding to the IL-12Rβ1 receptor chain of IL-12 (IL-12Rβ1/β2) and IL-23 (IL-12Rβ1/23R) receptor complexes on the surface of natural killer cells and T-cells[1]. Ustekinumab is a human IgG1 kappa (κ) monoclonal antibody against the IL-12/IL-23 p40 subunit that prevents its interaction with IL-12Rβ1, thereby blocking subsequent signaling. The FcRn affinities at pH 6.0 fell in a narrow range for all 11 antibodies. The equilibrium dissociation constant (KD) is calculated relative to Ustekinumab (Ustekinumab=1.0)[2].

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