Adalimumab
CAS No. : 331731-18-1
(Synonyms: Anti-Human TNF-alpha, Human Antibody)
| Size | Price | Stock |
|---|---|---|
| 1mg | $280 | In-stock |
| 5mg | $670 | In-stock |
| 10mg | $1150 | In-stock |
| 25mg | $2550 | In-stock |
| 50mg | $4080 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-P9908 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Adalimumab is a human monoclonal IgG1 antibody targeting tumour necrosis factor α (TNF-α).
IC50 & Target:TNF-α[1]
In Vitro: Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study[2].
In Vivo: The elimination half-life (t1/2) of Adalimumab is long (~20 days)[1].
The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr-/- mice[2].
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