G3-C12 (TFA)


Price and Availability of HY-P1592A
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5mg $180 In-stock
10mg $280 In-stock
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Cat. No. : HY-P1592A
M.Wt: 1873.00
Formula: C74H115N23O23S2.C2HF3O2
Purity: >98 %
Solubility: H2O : ≥ 50 mg/mL
Introduction of G3-C12 (TFA) :

G3-C12 (TFA) is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. IC50 & Target: Kd: 88 nM (Galectin-3)[1]. In Vitro: G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 (TFA) bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer[1].

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