β-CGRP, human (TFA)
(Synonyms: Human β-CGRP (TFA); CGRP-II (Human) (TFA))
| Size | Price | Stock |
|---|---|---|
| 500μg | $150 | Get quote |
| 1mg | $270 | In-stock |
| 5mg | $940 | In-stock |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-P1548A |
| M.Wt: | 1000.00 |
| Formula: | C162H267N51O48S3.xC2HF3O2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
β-CGRP, human TFA (Human β-CGRP TFA) is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells[1]. IC50 & Target:IC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay)[1] In Vitro: β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 nM in NG108-15 and HEK293T cells expressing CRLR and RAMP2[1]. CGRP is a potent vasodilator and also shows pro- and -anti-inflammatory activity[2].
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- β-CGRP, human (TFA)
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