| Size | Price | Stock |
|---|---|---|
| 100μg | $250 | Get quote |
| 200μg | $400 | Get quote |
| 500μg | $750 | Get quote |
| 1mg | $1280 | Get quote |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-P1407 |
| M.Wt: | 1000.00 |
| Formula: | C31H49FN10O6·xC2HF3O2 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic;warming) |
Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA is an irreversible MALT1 protein inhibitor. Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone TFA inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression[1][2].
In Vitro:Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone (Compound Z-VRPR-FMK) (50 μM, 24 h) TFA can effectively reduce the level of c-REL in the nucleus of HBL-1 cells and inhibit the signal transduction of NF-κB[2].
Z-Val-Arg-Pro-DL-Arg-Fluoromethylketone (50 μM, 48 h) TFA can inhibit the proliferation of ABC-DLBCL cell lines HBL-1, TMD8, OCI-Ly3 and OCI-Ly10[2].
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