Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA)


(Synonyms: Atrial natriuretic factor (1-28) (rat, mouse) (TFA))

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500μg $180 Get quote
1mg $280 In-stock
5mg $980 In-stock
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Cat. No. : HY-P1236A
M.Wt: 3176.43
Formula: C130H206N45F3O41S2
Purity: >98 %
Solubility: H2O
Introduction of Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) :

Atrial Natriuretic Peptide (ANP) (1-28), rat, mouse (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. IC50 & Target:Endothelin-1[1] In Vitro: Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].

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