Glucagon-like peptide 1 (1-37), human (TFA)
(Synonyms: HuGLP-1 (TFA))
| Size | Price | Stock |
|---|---|---|
| 500μg | $270 | Get quote |
| 1mg | $440 | In-stock |
| 5mg | $880 | In-stock |
| 10mg | $1280 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-P1145A |
| M.Wt: | 1000.00 |
| Formula: | C186H275N51O59.xC2HF3O2 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (5.84 mM; Need ultrasonic) |
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor. IC50 & Target:GLP-1 receptor[1]. In Vitro: Glucagon-like peptide-1 (GLP-1) is produced by the posttranslational processing of proglucagon and acts as a regulator of various homeostatic events. GLP-1(1-37) is more stable than GLP-1(7-37), with 94.7% of the initial amount of peptide left after a 4h exposure to mouse serum. GLP-1(1-37) is confirmed to be a highly potent agonist of the GLP-1 receptor (GLP-1R) by measuring the expression of the luciferase reporter gene expression in transiently transfected human embryonic kidney (HEK293) cells[1]. In Vivo: GLP-1(1–37) decreases glycemic excursion in a dose-dependent. The administration of GLP-1(1–37) or GLP-1(7–37) markedly decrease blood glucose levels at 15 min and 30 min compared with the control group[1].
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- Glucagon-like peptide 1 (1-37), human (TFA)
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- HY-P1145A
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