L-JNKI-1


Price and Availability of HY-P0069A
Size Price Stock
5mg $240 In-stock
10mg $360 In-stock
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Cat. No. : HY-P0069A
M.Wt: 3822.44
Formula: C164H286N66O40
Purity: >98 %
Solubility: H2O : ≥ 100 mg/mL
Introduction of L-JNKI-1 :

L-JNKI-1 is a cell-permeable peptide inhibitor specific for JNK. IC50 & Target:JNK[1]. In Vivo: L-JNKI-1 has been shown to effectively inhibit JNK activity in in vivo studies. It is shown that Ang II induces a dose-dependent pressor response, which was significantly attenuated by JNK inhibition[1]. It is also found that 10 μM L-JNKI-1 decreases phosphorylated c-Jun by 98% and phosphorylated Elk-1 by 100%. L-JNKI-1 is able to across the blood-brain barrier and penetrate neurons of adult mice and P5 rats within 1 h after an intraperitoneal injection[2].

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