Ac-Exatecan
CAS No. : 2922852-48-8
| Size | Price | Stock |
|---|---|---|
| 10mg | $35 | In-stock |
| 25mg | $65 | In-stock |
| 50mg | $95 | In-stock |
| 100mg | $140 | In-stock |
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| Cat. No. : | HY-79490 |
| M.Wt: | 477.48 |
| Formula: | C26H24FN3O5 |
| Purity: | >98 % |
| Solubility: |
Ac-Exatecan is acetylation-modified Exatecan (HY-13631). Exatecan is a common toxin component in ADC preparation (ADC cytotoxin) and an inhibitor of DNA topoisomerase I (IC50 = 2.2 μM). Exatecan has antitumor activity. Exatecan can be used as a payload for ADC. Exatecan is effective against P-glycoprotein mediated multi-drug resistant cells[1][2].
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