ML241 (hydrochloride)
CAS No. : 2070015-13-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $96 | In-stock |
| 25mg | $195 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $450 | In-stock |
| 200mg | $630 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-19797A |
| M.Wt: | 408.92 |
| Formula: | C23H25ClN4O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 34 mg/mL;H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
ML241 hydrochloride is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 value of 100 nM. IC50 & Target:IC50: 100 nM (p97)[1] In Vitro: ML241 hydrochloride is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 values of 100 nM. ML241 inhibits p97 competitively with respect to ATP with a Ki values of 0.35 μM. ML241 (20 μM) shows no obvious inhibition of the appr 170 kinases tested. ML241 stabilizes UbG76V-GFP with IC50 of 3.5 μM[1]. ML241 is cytotoxic to HCT15 and SW403 cells, with GI50s of 53 and 33 μM after treatment for 24 h, and 13 and 12 μM after treatment for 72 h, respectively[2].
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