IFN alpha-IFNAR-IN-1 (hydrochloride)
CAS No. : 2070014-98-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $119 | In-stock |
| 10mg | $158 | In-stock |
| 50mg | $422 | In-stock |
| 100mg | $739 | In-stock |
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| Cat. No. : | HY-12836A |
| M.Wt: | 315.86 |
| Formula: | C18H18ClNS |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 16.67 mg/mL (ultrasonic) |
IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3- L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM)[1].
In Vitro:IFN alpha-IFNAR-IN-1 (compound 1) (18 μM; 24 h) hydrochloride specifically inhibits MVA-induced IFN-a responses by BMpDCs[1].
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