DJ4
CAS No. : 1681020-24-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $88 | In-stock |
| 10mg | $137 | In-stock |
| 25mg | $266 | In-stock |
| 50mg | $393 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-125221 |
| M.Wt: | 348.42 |
| Formula: | C19H16N4OS |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
DJ4 is a ATP-competitive inhibitor of ROCK1/2 (IC50 values:5 and 50 nM) and MRCKα/β (IC50 values:10 and 100 nM). DJ4 blocks stress fiber formation and inhibits migration and invasion of cancer cells. DJ4 can be used for study of lung cancer, breast cancer, and pancreatic (PANC-1) cancer[1].
In Vitro:DJ4 (2.5-5 µM; 24 h) inhibits migration and invasion of cancer cells[1].
DJ4 (2.5-5 µM; 24 h) blocks recombinant MYPT1 phosphorylation in A549 cells[1].
A549 cells[1]
2.5 µM, 5 µM
24 h
Effectively blocked recombinant MYPT1 phosphorylation.
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