PARP11 inhibitor ITK7
CAS No. : 2411890-36-1
(Synonyms: ITK7)
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $510 | In-stock |
| 50mg | $834 | In-stock |
| 100mg | $1335 | In-stock |
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| Cat. No. : | HY-125218 |
| M.Wt: | 322.38 |
| Formula: | C17H14N4OS |
| Purity: | >98 % |
| Solubility: | DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C) |
PARP11 inhibitor ITK7 (ITK7) is a potent and selective PARP11 inhibitor. PARP11 inhibitor ITK7 can potently inhibit PARP11 with an IC50 value of 14 nM. PARP11 inhibitor ITK7 can be used for the research of cellular localization[1].
IC50 & Target:IC50: 14 nM (PARP11); 13 nM (PARP11-dependent auto-MARylation)[1]
In Vitro:PARP11 inhibitor ITK7 (ITK7) can potently inhibit PARP11 with an IC50 value of 14 nM[1].
ITK7 exhibits a dose-dependent inhibition of PARP11-dependent auto-MARylation with an EC50 value of 13 nM[1].
ITK7 (0, 0.03, 0.1, 0.3, 1, 3 μM; 3 h) inhibits PARP11 auto-MARylation activity in cells and causes PARP11 to dissociate from the nuclear
envelope[1].
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