(3S,5S,6R)-Navtemadlin
CAS No. : 2459946-14-4
(Synonyms: (3S,5S,6R)-AMG 232; (3S,5S,6R)-KRT-232)
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $195 | In-stock |
| 25mg | $390 | In-stock |
| 50mg | $620 | In-stock |
| 100mg | $920 | In-stock |
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| Cat. No. : | HY-12296A |
| M.Wt: | 568.55 |
| Formula: | C28H35Cl2NO5S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
(3S,5S,6R)-Navtemadlin is the isomer of Navtemadlin (HY-12296), and can be used as an experimental control. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].
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