XL 188


CAS No. : 2305045-76-3

2305045-76-3
Price and Availability of CAS No. : 2305045-76-3
Size Price Stock
1mg $40 In-stock
5mg $94 In-stock
10mg $160 In-stock
25mg $340 In-stock
50mg $544 In-stock
100mg $870 In-stock
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Cat. No. : HY-122886
M.Wt: 574.71
Formula: C32H42N6O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 2305045-76-3 :

XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1]. In Vitro:XL 188 (1-20 μM; 16 h; MCF7 cells) promotes USP7 dependent loss of HDM2 and increase of p53 and p21[1].

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