HS-131
CAS No. : 2084850-40-6
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| Cat. No. : | HY-122878 |
| M.Wt: | 1318.68 |
| Formula: | C71H95N7O13S2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers[1].
In Vivo: HS131 (10 nmol/mouse) could label breast cancers with different molecular subtypes, including MCF-7 and T-47D for luminal type, BT474M1 and KPL-4 for HER2+ subtype, MDA-MB-231 and MDA-MB-468 for triple negative subtype were chosen after considering the tumorigenic capacities of breast cancer cell lines in SCID mice[1].
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