CHMFL-KIT-031


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Cat. No. : HY-122849
M.Wt: 487.51
Formula: C26H25N5O5
Purity: >98 %
Solubility:
Introduction of CHMFL-KIT-031 :

CHMFL-KIT-031 is a highly selective KIT V559D inhibitor, with an IC50 of 28 nM. CHMFL-KIT-031 potently affects KIT V559D mutant’s phosphorylation at Y703/719/823 sites. CHMFL-KIT-031 inhibits the tumor growth in BaF3-TEL-KIT-V559D cell inoculated mouse model[1]. IC50 & Target:IC50: 28 nM (KIT V559D); 168 nM (KIT wt)[1].

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