ABC99
CAS No. : 2331255-53-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $150 | In-stock |
| 5mg | $300 | In-stock |
| 10mg | $450 | In-stock |
| 25mg | $800 | In-stock |
| 50mg | $1200 | In-stock |
| 100mg | $1665 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-122832 |
| M.Wt: | 456.88 |
| Formula: | C22H21ClN4O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;heat to 80°C) |
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM[1].
IC50 & Target:IC50: 13 nM (Notum)[1]
In Vitro: ABC99 (0.1~10 μΜ; 2 hours; SW620 cells) inhibits NOTUM in a concentration-dependent manner[1].
ABC99 preserves Wnt-3A activity in the presence of NOTUM in a concentration-dependent manner[1].
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