CM-579 trihydrochloride
CAS No. : 2448471-08-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $230 | In-stock |
| 50mg | $370 | In-stock |
| 100mg | $580 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-117421A |
| M.Wt: | 602.04 |
| Formula: | C29H43Cl3N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic);H2O : 37.5 mg/mL (ultrasonic) |
CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells[1]. In Vitro: The Kd of CM-579 for DNMT1 is 1.5 nM, CM-579 also inhibits DNMT3A and DNMT3B, with IC50s of 92 nM and 1000 nM, respectively[1].
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