Erasin


CAS No. : 2256056-21-8

2256056-21-8
Price and Availability of CAS No. : 2256056-21-8
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5mg $90 In-stock
10mg $150 In-stock
25mg $300 In-stock
50mg $480 In-stock
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Cat. No. : HY-115594
M.Wt: 349.38
Formula: C20H19N3O3
Purity: >98 %
Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 2256056-21-8 :

Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis[1]. In Vitro: Erasin inhibits protein-protein interactions mediated by STAT SH2 domains[1].
Erasin (0-80 μM; 24 h) induces apoptosis in MDA-MB-231, HCC-827 and Erlotinib (HY-50896)-resistant HCC-827 cells[1].

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