YLT-11
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-115589 |
| M.Wt: | 412.49 |
| Formula: | C24H24N6O |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
YLT-11 is a potent, selective and orally active PLK4 inhibitor with Kd values of >10000, 653, >10000, 5.2 nM for PLK1, PLK2, PLK3, PLK4, respectively. YLT-11 shows antiproliferative activity. YLT-11 induces Apoptosis and cell cycle arrest at G2/M phase. YLT-11 show anticancer activity[1].
In Vitro:YLT-11 (0-1 µM; 48 h) decreases the expression of p-PLK4 in a dose-dependent manner[1].
YLT-11 (0-0.5 µM; 0-48 h) induces apoptosis and cell cycle arrest at G2/M phase[1].
In Vivo:YLT-11 (30, 90 mg/kg; p.o.; daily for 20 days) shows anti-cancer activity in mice[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- YLT-11
- Cat. No.:
- HY-115589
- Quantity:
Your information is safe with us.