TRPV4 agonist-1 (free base)
CAS No. : 2314467-59-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $160 | In-stock |
| 50mg | $266 | In-stock |
| 100mg | $440 | In-stock |
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| Cat. No. : | HY-114400 |
| M.Wt: | 448.46 |
| Formula: | C25H22F2N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 83.33 mg/mL (ultrasonic) |
TRPV4 agonist-1 free base is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1]. IC50 & Target: EC50: 60 nM (hTRPV4 hTRPV4 Ca2+)[1] In Vitro: TRPV4 agonist-1 (Compound 36) exhibits significantly increased potency (ECmax: 20 nM in the SOX9 reporter assay). TRPV4 agonist-1 is inactive against TRPV1 channels[1].
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