NVS-ZP7-4
CAS No. : 2349367-89-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $195 | In-stock |
| 10mg | $340 | In-stock |
| 25mg | $680 | In-stock |
| 50mg | $1080 | In-stock |
| 100mg | $1660 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-114395 |
| M.Wt: | 501.62 |
| Formula: | C28H28FN5OS |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7) and indicates ER zinc levels. ZIP7 is an active molecular node in the Notch pathway and mediates ferroptosis. NVS-ZP7-4 induces ER stress and exerts a certain ferroptosis-inhibiting effect, reduces Erastin (HY-15763)-induced cell death[1][2]. IC50 & Target:ZIP7[1]. In Vitro:NVS-ZP7-4 increases ER zinc levels, suggesting functional modulation of ZIP7[1].
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