MARK4 inhibitor 1
CAS No. : 2271081-58-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $330 | In-stock |
| 10mg | $490 | In-stock |
| 25mg | $890 | In-stock |
| 50mg | $1250 | In-stock |
| 100mg | $1950 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-114317 |
| M.Wt: | 390.40 |
| Formula: | C20H18N6O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;adjust pH to 2 with HCl) |
MARK4 inhibitor 1 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1].
IC50 & Target:IC50: 1.54 μM (MARK4)[1].
In Vitro:MARK4 inhibitor 1 (compound 9g; 0-200 µM ; 24-48 h) shows inhibition of cell proliferation and cell migration[1].
MARK4 inhibitor 1 (compound 9g; 24) induces apoptosis in these cancerous cells, with IC50 values of 6.22 μM, 9.94 μM and 8.14 μM, respectively[1].
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