BA-53038B
CAS No. : 2306195-65-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $200 | In-stock |
| 10mg | $320 | In-stock |
| 25mg | $640 | In-stock |
| 50mg | $980 | In-stock |
| 100mg | $1350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-114314 |
| M.Wt: | 249.74 |
| Formula: | C14H16ClNO |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B has antiviral activity for hepatitis B virus (HBV) with an EC50 value of 3.32 μM. BA-53038B can be used for the research of chronic hepatitis B[1].
IC50 & Target:EC 50: 3.32 μM (HBV)[1]
In Vitro:BA-53038B has antiviral activity for HBV with an EC50 value of 3.32 μM[1].
BA-53038B has cytotoxicity with CC50 value of >100 μM[1].
BA-53038B (5 μM; 48 h) induces the capsid/nucleocapsid mobility shift and reduced the amount of hypophosphorylated core protein[1].
BA-53038B (0-20 μM; 2 or 6 days) inhibits HBV nucleocapsid assembly[1].
BA-53038B (5 μM; 2 days) inhibits pgRNA encapsidation and consequentially reduces the amount of DNA-containing capsids and hypophosphorylated core protein[1].
BA-53038B (2 μM; 6 h) modulates HBV capsid assembly by binding to the HAP pocket[1].
BA-53038B has resistant effect with an EC50 value of >10 μM on HBV capsid (HepG2 cells transiently transfected pHBV1.3/core-V124W)[1].
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