VDR agonist 1
CAS No. : 2269494-43-9
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| Cat. No. : | HY-114310 |
| M.Wt: | 509.77 |
| Formula: | C32H51N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
VDR agonist 1 (compound 28) is a nonsteroidal Vitamin D receptor (VDR) agonist, with an IC50 of 690 nM in MCF-7 cells. VDR agonist 1 arrests the cell cycle through the up-regulation of p21 and p27, promotes apoptosis by increasing the expression of BAX and decrease the expression of Bcl-2[1]. IC50 & Target: IC50: 690 nM (VDR in MCF-7 cells)[1].
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