PROTAC BET degrader-3
CAS No. : 3031993-61-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $220 | In-stock |
| 5mg | $550 | In-stock |
| 10mg | $850 | In-stock |
| 25mg | $1850 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-114229 |
| M.Wt: | 1045.22 |
| Formula: | C53H64N12O9S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
PROTAC BET Degrader-3 (Example C-55) is a BET PROTAC degrader and can be used in cancer research[1]. IC50 & Target:BET[1] In Vitro:BET acts as an "reader" for epigenetics, regulating gene transcription by interacting with acetylated histones. BET is highly expressed in various hematological malignancies (such as acute myeloid leukemia AML, T-cell acute lymphoblastic leukemia T-ALL) and solid tumors, promoting the proliferation, survival, and metastasis of cancer cells. BET PROTAC Degrader demonstrates stronger anti-tumor activity and the potential to overcome drug resistance through protein degradation rather than simple inhibition[1].
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