PF-06928215


CAS No. : 2378173-15-8

2378173-15-8
Price and Availability of CAS No. : 2378173-15-8
Size Price Stock
5mg $231 In-stock
10mg $340 In-stock
25mg $640 In-stock
50mg $960 In-stock
100mg $1400 In-stock
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500 mg Get quote
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Cat. No. : HY-114182
M.Wt: 380.40
Formula: C20H20N4O4
Purity: >98 %
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Introduction of 2378173-15-8 :

PF-06928215 is a cGAS (cyclic GMP-AMP Synthase) inhibitor with an IC50 of 4.9 μΜ. PF-06928215 has a high binding affinity of 0.2 μM (Kd)[1]. IC50 & Target: IC50: 4.9 μM (cGAS)[1]
Kd: 0.2 μM[1] In Vitro: PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression[1].

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