H-Val-Pro-Pro-OH (TFA)


CAS No. : 2828433-08-3

2828433-08-3
Price and Availability of CAS No. : 2828433-08-3
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10mg $70 In-stock
25mg $120 In-stock
50mg $190 In-stock
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Cat. No. : HY-114161A
M.Wt: 425.40
Formula: C17H26F3N3O6
Purity: >98 %
Solubility: H2O : 125 mg/mL (ultrasonic)
Introduction of 2828433-08-3 :

H-Val-Pro-Pro-OH (TFA), a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM. IC50 & Target:IC50: 9 μM (ACE)[1]. In Vitro: H-Val-Pro-Pro-OH (TFA), a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC50 of 9 μM[1]. H-Val-Pro-Pro-OH (TFA) could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH (TFA) also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH (TFA) further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes[2].

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