CCR6 inhibitor 1
CAS No. : 2437547-04-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $360 | In-stock |
| 10mg | $540 | In-stock |
| 50mg | $1188 | In-stock |
| 100mg | $1660 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-112701 |
| M.Wt: | 504.52 |
| Formula: | C24H23F3N4O3S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1]. IC50 & Target: IC50: 0.45 nM (Moneky CCR6), 6 nM (Human CCR6), 9400 nM (Human CCR7)[1] In Vitro: CCR6 inhibitor 1 (Compound 35) inhibits L20-induced human B cell migration[1].
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