SHIP2-IN-1


CAS No. : 2252247-80-4

2252247-80-4
Price and Availability of CAS No. : 2252247-80-4
Size Price Stock
5mg $350 In-stock
10mg $550 In-stock
25mg $950 In-stock
50mg $1450 In-stock
100mg $2250 In-stock
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Cat. No. : HY-112700
M.Wt: 379.22
Formula: C17H13Cl2FN4O
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 2252247-80-4 :

SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC50 of 2 µM. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer’s disease[1]. IC50 & Target: IC50: 2 µM (SHIP2)[1] In Vitro: SHIP2-IN-1 (Compound 43; 10 µM) significantly inhibits PI(3,4)P2 production in HT22 cells[1].

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