MC3482


CAS No. : 2922280-86-0

2922280-86-0
Price and Availability of CAS No. : 2922280-86-0
Size Price Stock
5mg $140 In-stock
10mg $230 In-stock
25mg $360 In-stock
50mg $570 In-stock
100mg $920 In-stock
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500 mg Get quote
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Cat. No. : HY-112587
M.Wt: 618.68
Formula: C33H38N4O8
Purity: >98 %
Solubility: DMSO : ≥ 130 mg/mL
Introduction of 2922280-86-0 :

MC3482 is a specific sirtuin5 (SIRT5) inhibitor. IC50 & Target:SIRT5[1] In Vitro: MC3482 inhibits sirtuin5. 50 μM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-overexpressing cells[1].

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