BAY885
CAS No. : 2307249-33-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $58 | In-stock |
| 5mg | $200 | In-stock |
| 10mg | $300 | In-stock |
| 25mg | $540 | In-stock |
| 50mg | $810 | In-stock |
| 100mg | $1215 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-112082 |
| M.Wt: | 515.53 |
| Formula: | C25H28F3N7O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 16.67 mg/mL (ultrasonic) |
BAY885 is a highly potent and selective ERK5 inhibitor with an IC50 of 35 nM. BAY885 shows weak inhibition on others kinases[1]. In Vitro: The ERK5 probe 41 (BAY-885) showed potent ERK5 kinase and transcriptional inhibition in the SN12C-MEF2 reporter cell line (IC50 = 115 nM/IC90 = 691 nM) and had no effects on a reporter control cell line with constitutive luciferase expression (SN12C-CMV-luc, IC50 > 30 μM)[1].
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