| Size | Price | Stock |
|---|---|---|
| 1mg | $80 | In-stock |
| 5mg | $172 | In-stock |
| 10mg | $275 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $880 | In-stock |
| 100mg | $1300 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-111674 |
| M.Wt: | 349.38 |
| Formula: | C20H19N3O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages [1].
IC50 & Target: Gasdermin D[1].
In Vitro: LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells[3].
LDC7559 functions directly through blocking the activity of the GSDMD NT domain, rather than interfering with the activation and cleavage process[3].
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